Qatar has insufficient water resources and poor soil conditions. Sustainable development is contingent on Qatar’s ability to achieve reasonable water and food security. Qatar currently relies heavily on food imports (90%); meeting future food needs require consideration of diverse options. Treated wastewater (reclaimed water) presents a viable renewable water source capable of augmenting existing but limited groundwater reserves (water security). Likewise, controlled-environment agriculture systems (i.e., greenhouse hydroponics) can help meet local demands (food security), especially for high-value agricultural crops (e.g., vegetables, fruits). Our major goal is to determine the suitability of reclaimed water from Qatar’s municipal wastewater systems for use in greenhouse hydroponics. Specific focus will be on emerging chemical contaminants (pharmaceuticals and personal care products, PPCPs), which in principle could limit the acceptability of reclaimed water use. We will perform baseline source characterization of well-known chemicals of emerging concern (CECs) in reclaimed waters and extent of CEC uptake by plants (roots, shoots, leaves) grown in greenhouse hydroponic systems. Tests will include diverse plants (carrot, spinach, tomato) and CECs varying in chemical characteristics (polarity, charge). Project results will help determine suitability of long-term use of reclaimed water for vegetable production using controlled-environment agricultural systems in Qatar.