Project Tags: Biological Sciences

Investigating PARP inhibition in colorectal cancer cell lines and combinatorial approaches to improve sensitivity

Colorectal cancer (CRC) still ranks as one of the most common cancers and a leading cause of cancer-related death worldwide and in Qatar, despite significant advances in surveillance and treatment.…

Investigating the role of deregulated minor intron splicing in cancer-related genes

Minor intron splicing in breast cancer was studied in two previous funded projects (NPRP and Seed). Data from these projects laid the foundation for the current proposal as they identified…

Studying the Molecular Mechanism of Integrin-specific Response to Kindlin Overexpression in Adherent Cells

Integrins form a large family of transmembrane cell adhesion receptors, formed by β heterodimers and involved in different physiological processes such as hemostasis, cell migration, and pathological conditions like cancer,…

Delineating the Role of Cancer-associated Fibroblasts in Solid Tumors

Skin cancer continues to be one of the top leading causes of mortality in Qatar (Qatar Cancer Society, 2015). Central to the tumor microenvironment is the predominance of cancer-associated fibroblasts…

Innova ve Hybrid Plasmonic Metal Nanopar cles: Synthesis, Characteriza on, and Explora on of their Stability and Cytotoxicity for Advanced Biosensors.

The early diagnosis of diseases requires sensitive detection methods for biological molecules, known as biomarkers. This research focuses on the potential breakthrough offered by plasmonic nanoparticles, specifically silver-based nanoparticles. Unlike…

Biological conversion of fuel synthesis process water to single cell protein for aquaculture feed using purple phototrophic bacteria

Qatar has limited freshwater resources and arable land. As a result, fisheries have long played an important role in sustaining the nutritional requirements of Qatar’s population. Under Qatar’s rapid industrial…

Using bacteriophages as biomonitoring tools for water quality measurements

Water security and sustainability in Qatar is a critical issue. The only source of drinking water is the desalinated seawater from the Arabian Gulf. The storage capacity for emergency use…

Sustainable bioplastics production from industrial wastewaters using photosynthetic microbial production of polyhydroxyalkanoates (PHAs)

Plastics, due to their light weight, low cost and ease of processing have become the material of the 21st century, but this tremendous growth has also resulted in many environmental…

Exploring neuronal and non-neuronal defects associated with neurodevelopmental disorders

Many pathogenic mutations related to neurodevelopmental diseases are associated with both neuronal and non-neuronal features, however functional characterization and validations have mainly focused on the molecular basis of neuronal defects.…

Development of Novel Antibiotic, Antiparasitic, and Anticancer Agents

Thymidylate kinases (TMKs) play a central role in the production of nucleotide precursors that are required for the replication of DNA. Consequently, this enzyme is a potential drug target for…